The paper gives data available in the literature on the use of citicoline in an experimental model of ischemic stroke (IS) and in randomized multicenter placebo-controlled trials. It analyzes the results of the ICTUS trial in which 2298 patients with IS who received randomly citicoline or placebo for 24 hours after the onset of symptoms (I000 mg intravenously every I2 hours during the... https://www.remtavares.com/