[114] Activation on the ECS system in MS (and EAE) appears to limit neuronal destruction by downregulation of cannabinoid receptors inhibiting GABA synapses as being a protective motion to reduce neuronal excitotoxic problems. Upregulation of endocannabinoid tone shields neurons from excitotoxicity in parallel that has a therapeutic effect inside of https://carcrashcompensation81100.blogs-service.com/63758817/the-psychoactive-effects-diaries