Docking scientific studies of 14b and 14c with the ATP-binding pocket of FGFR1 (4ZSA) revealed the N–H from the indazole ring fashioned a hydrogen bond with Glu562, Whilst the nitrogen atom with the indazole group and N–H in the amide bond fashioned a hydrogen bond with Ala564. Utilizing DFT Evaluation, https://jaspervoetj.blogunteer.com/30317426/the-smart-trick-of-indazole-pka-that-no-one-is-discussing